Adrenocortical Carcinoma Treatment (PDQ®)

Cancer Information Summaries « English « Health professionals « A

Recurrent Adrenocortical Carcinoma

The question and selection of further treatment for patients with adrenocortical carcinoma depends on many factors, including previous treatment and site of recurrence as well as individual patient considerations. Local recurrence and selected sites of metastatic disease can sometimes be palliated by surgery. Although none of these patients can be considered curable, palliation of hormonal symptoms and occasional 5-year survivals can be achieved. [1] [2] Substantial morbidity, however, is associated with resection of these recurrent tumors. [2] Clinical trials, such as ECOG-1879and SWOG-8325, are appropriate and should be considered whenever possible, especially phase I and II trials that evaluate newer chemotherapeutic and biological agents. [3] [4] [5] [6] [7]

Current Clinical Trials

Check for U.S. clinical trials from NCI’s PDQ Cancer Clinical Trials Registry that are now accepting patients with recurrent adrenocortical carcinoma. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.

General information about clinical trials is also available from the NCI Web site.

This record was last updated on May 16th, 2008.


About the PDQ Cancer Information Summaries from the National Cancer Institute

PDQ (Physician Data Query) is a comprehensive cancer database published by the National Cancer Institute (NCI), which is part of the National Institutes of Health (NIH). It contains peer-reviewed summaries on cancer treatment, screening, prevention, genetics, and supportive care, and complementary and alternative medicine; a registry of cancer clinical trials; and directories of physicians, professionals who provide genetics services, and organizations that provide cancer care.

The PDQ Cancer Information Summaries are peer reviewed and updated monthly by six editorial boards comprised of specialists in adult treatment, pediatric treatment, supportive care, screening and prevention, genetics, and complementary and alternative medicine. The Boards review current literature from more than 70 biomedical journals, evaluate its relevance, and synthesize it into clear summaries. Many of the summaries are also available in Spanish.

Linked medical terms appearing on this page are added by Healia to help readers find more information and are not part of the original PDQ document.

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