Lupus is a chronic autoimmune disease that causes inflammation in any of several areas throughout the body including the joints, skin, kidneys, blood vessels, heart, lungs, and nervous system. When one of these areas is affected, it causes symptoms that range from pain or discomfort in the area all the way to organ dysfunction and failure. The most common and serious type of lupus is systemic lupus erythematosus (SLE).

Current figures estimate that around 1.5 million Americans have lupus, but the actual number may be higher. More than 90% of people with lupus are women. The disease usually starts between ages 15 and 44 but can affect people at any age.

For most people with lupus, the disease is mild, affecting only a few organs. For others, it may cause serious complications that may become life-threatening. The prognosis for lupus has improved greatly in the recent past and while the disease may still be fatal for some, with treatment, most people with lupus can lead full, active lives.